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PRAS40 Products

PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.

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52 results for "PRAS40" in Products

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52 results for "PRAS40" in Products

PRAS40 Products

PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.

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Applications: WB, ICC
Reactivity: Human, Mouse
Applications: WB, Simple Western, ICC
Reactivity: Human
Applications: IHC
Reactivity: Human
Applications: WB
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, IP
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB, IP
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human, Mouse
Applications: IHC, WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: IHC
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody

Applications: AC
Applications: ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Drosophila
Applications: WB
Applications: WB
Applications: IHC
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
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