PRDM16/MEL1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-71992

Novus Biologicals, part of Bio-Techne
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NBP1-71992
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PRDM16/MEL1 Antibodies »

Product Specifications

Immunogen

A 17 aa synthetic peptide near the C-terminus of human PRDM16/MEL1. The immunogen is located within aa 1120 - 1170 of PRDM16/MEL1.

Epitope

C-Terminus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRDM16/MEL1 Antibody - BSA Free

Western Blot: PRDM16/MEL1 AntibodyBSA Free [NBP1-71992]

Western Blot: PRDM16/MEL1 AntibodyBSA Free [NBP1-71992]

Western Blot: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992] - Analysis of anti-PRDM16 antibody with rat brain tissue lysate.
Immunohistochemistry-Paraffin: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992]

Immunohistochemistry-Paraffin: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992]

Immunohistochemistry-Paraffin: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992] - Analysis of anti-PRDM16 antibody with human skin at concentration 5 ug/ml.
Immunocytochemistry/ Immunofluorescence: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992]

Immunocytochemistry/ Immunofluorescence: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992]

Immunocytochemistry/Immunofluorescence: PRDM16/MEL1 Antibody - BSA Free [NBP1-71992] - Analysis of anti-PRDM16 antibody with human brain cells.

Applications for PRDM16/MEL1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRDM16/MEL1

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

PR Domain Containing 16

Alternate Names

MDS1/EVI1-like gene 1, MEL1, PFM13

Gene Symbol

Prdm16

Additional PRDM16/MEL1 Products

Product Documents for PRDM16/MEL1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PRDM16/MEL1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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