PRDM16/MEL1 Antibody [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77096H

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-77096AF350

Alexa Fluor 405

NBP1-77096AF405

Alexa Fluor 488

NBP1-77096AF488

Alexa Fluor 532

NBP1-77096AF532

Alexa Fluor 594

NBP1-77096AF594

Alexa Fluor 647

NBP1-77096AF647

Alexa Fluor 700

NBP1-77096AF700

Alexa Fluor 750

NBP1-77096AF750

Biotin

NBP1-77096B

CoraFluor 1

NBP1-77096CL1

DyLight 350

NBP1-77096UV

DyLight 405

NBP1-77096V

DyLight 488

NBP1-77096G

DyLight 550

NBP1-77096R

DyLight 594

NBP1-77096DL594

DyLight 650

NBP1-77096C

DyLight 680

NBP1-77096FR

DyLight 755

NBP1-77096IR

FITC

NBP1-77096F

Janelia Fluor 525

NBP1-77096JF525

Janelia Fluor 549

NBP1-77096JF549

Janelia Fluor 646

NBP1-77096JF646

Janelia Fluor 669

NBP1-77096JF669

mFluor Violet 450 SE

NBP1-77096MFV450

mFluor Violet 500 SE

NBP1-77096MFV500

mFluor Violet 610 SE

NBP1-77096MFV610

PerCP

NBP1-77096PCP

Forumulation

Catalog #

BSA Free

NBP1-77096

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

HRP

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRDM16/MEL1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16. The immunogen is located within amino acids 1120 - 1170 of PRDM16. Amino Acid Squence: AGKSQDDTVSPAPEPQA

Reactivity Notes

0

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for PRDM16/MEL1 Antibody [HRP]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PRDM16/MEL1

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

PR Domain Containing 16

Alternate Names

MDS1/EVI1-like gene 1, MEL1, PFM13

Gene Symbol

Prdm16

Additional PRDM16/MEL1 Products

Product Documents for PRDM16/MEL1 Antibody [HRP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PRDM16/MEL1 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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