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PRELP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25069

Novus Biologicals, part of Bio-Techne
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NBP3-25069

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein PRELP using the following amino acid sequence: GLRWINLDNNRIRKIDQRVLEKLPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRELP Antibody

PRELP Antibody Immunocytochemistry/Immunofluorescence: PRELP Antibody [NBP3-25069]

Immunocytochemistry/Immunofluorescence: PRELP Antibody [NBP3-25069]

Staining of human cell line U2OS shows localization to endoplasmic reticulum.

Applications for PRELP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRELP

PRELP is encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Long Name

Proline-arginine-Rich End Leucine-rich repeat Protein

Alternate Names

MST161, MSTP161, Prolargin, SLRR2A

Gene Symbol

PRELP

Additional PRELP Products

Product Documents for PRELP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRELP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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