PRMT6 Antibody (1Z10L6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16549

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16549-100ul
NBP3-16549-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1Z10L6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRMT6 Antibodies »

Product Summary for PRMT6 Antibody (1Z10L6)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PRMT6 (Q96LA8). MLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRMT6 Antibody (1Z10L6)

Western Blot: PRMT6 Antibody (1Z10L6) [NBP3-16549]

Western Blot: PRMT6 Antibody (1Z10L6) [NBP3-16549]

Western Blot: PRMT6 Antibody (1Z10L6) [NBP3-16549] - Western blot analysis of extracts of various cell lines, using PRMT6 Rabbit mAb (NBP3-16549) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.

Applications for PRMT6 Antibody (1Z10L6)

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PRMT6

PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

Long Name

Protein arginine N-methyltransferase 6

Alternate Names

HRMT1L6

Gene Symbol

PRMT6

Additional PRMT6 Products

Product Documents for PRMT6 Antibody (1Z10L6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PRMT6 Antibody (1Z10L6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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