PRMT6 Antibody (SR1719)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22024

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22024-100ul
NBP3-22024-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1719

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRMT6 Antibodies »

Product Summary for PRMT6 Antibody (SR1719)

Immunogen

A synthesized peptide derived from human PRMT6 (Uniprot #: Q96LA8)

Specificity

Detects endogenous levels of total PRMT6

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRMT6 Antibody (SR1719)

Western Blot: PRMT6 Antibody (SR1719) [NBP3-22024] -

Western Blot: PRMT6 Antibody (SR1719) [NBP3-22024] - Western blot analysis using NBP3-22024 in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate; (3) C6 cell lysate.

Applications for PRMT6 Antibody (SR1719)

Application
Recommended Usage

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRMT6

PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

Long Name

Protein arginine N-methyltransferase 6

Alternate Names

HRMT1L6

Gene Symbol

PRMT6

Additional PRMT6 Products

Product Documents for PRMT6 Antibody (SR1719)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PRMT6 Antibody (SR1719)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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