Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-44105

Novus Biologicals, part of Bio-Techne
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NBP2-44105
NBP2-44105-0.05mg
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Lambda Clone # 4F2.D9.C5.G5.B2.C5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Procalcitonin Antibodies »

Product Specifications

Immunogen

Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5) was produced in mice prepared by repeated immunizations with full-length recombinant human Procalcitonin protein. (Uniprot: P06881)

Reactivity Notes

Cross-reactivity with Procalcitonin from other sources has not been determined

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 Lambda

Description

This antibody was purified from concentrated tissue culture supernate by Protein A chromatography

Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.

Scientific Data Images for Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5)

Western Blot: Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5) [NBP2-44105]

Western Blot: Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5) [NBP2-44105]

Western Blot: Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5) [NBP2-44105] - lane 1: MW. Lane 2: Procalcitonin Protein. Load: 5 Ug per lane.

Applications for Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:1000-1:2000
Application Notes
This product was tested by ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.

Background: Procalcitonin

Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.

Alternate Names

CALC1, CALCA, Calcitonin 1, calcitonin gene-related peptide 1, CGRP, Katacalcin

Gene Symbol

CALCA

UniProt

P06881 (Human)

Additional Procalcitonin Products

Product Documents for Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Procalcitonin Antibody (4F2.D9.C5.G5.B2.C5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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