Profilin 2 Antibody (5D4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43015

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5D4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Profilin 2 Antibodies »

Product Specifications

Immunogen

profilin 2 - (Uniprot# P35080)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Profilin 2 Antibody (5D4)

Profilin 2 Antibody (5D4)

Immunohistochemistry: Profilin 2 Antibody (5D4) [NBP3-43015] -

Immunohistochemistry: Profilin 2 Antibody (5D4) [NBP3-43015] - Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using (Profilin 2 Antibody) at dilution of 1:400
Profilin 2 Antibody (5D4)

Western Blot: Profilin 2 Antibody (5D4) [NBP3-43015] -

Western Blot: Profilin 2 Antibody (5D4) [NBP3-43015] - mouse brain tissue were subjected to SDS PAGE followed by western blot with (Profilin 2 Antibody) at dilution of 1:2000

Applications for Profilin 2 Antibody (5D4)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:500

Western Blot

1:1000 - 1:5000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Profilin 2

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung.

Alternate Names

D3S1319E, PFL, profilin 2, Profilin II, profilin-2

Gene Symbol

PFN2

Additional Profilin 2 Products

Product Documents for Profilin 2 Antibody (5D4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Profilin 2 Antibody (5D4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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