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Progesterone R/NR3C3 Antibody (PGR/8099R) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24086PE

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-24086PE

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # PGR/8099R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Progesterone R/NR3C3 Antibody (PGR/8099R) [PE]

Immunogen

Recombinant fragment (around aa 1-200) of human Progesterone R/NR3C3 (exact sequence is proprietary)

Localization

Nucleus.

Marker

Marker of Progestin Dependence

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for Progesterone R/NR3C3 Antibody (PGR/8099R) [PE]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Progesterone R/NR3C3

The human Progesterone Receptor (PgR) is a member of the steroid family of nuclear receptors. PgR is found as a 120 kDa protein (Form B) or a 94 kDa protein (Form A) due to the use of alternative translation initiation sites. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription.

Long Name

Progesterone Receptor

Alternate Names

NR3C3, PGR, ProgesteroneR

Gene Symbol

PGR

Additional Progesterone R/NR3C3 Products

Product Documents for Progesterone R/NR3C3 Antibody (PGR/8099R) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Progesterone R/NR3C3 Antibody (PGR/8099R) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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