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Protein Disulfide Isomerase/P4HB Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41319

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Rabbit (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid peptide near the center of human Protein Disulfide Isomerase/P4HB. The immunogen is located within amino acids 190 - 240 of Protein Disulfide Isomerase/P4HB. Amino Acid Squence: FKKFDEGRNNFEGEVTK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Protein Disulfide Isomerase/P4HB Antibody - BSA Free

Western Blot: Protein Disulfide Isomerase/P4HB AntibodyBSA Free [NBP2-41319]

Western Blot: Protein Disulfide Isomerase/P4HB AntibodyBSA Free [NBP2-41319]

Western Blot: Protein Disulfide Isomerase/P4HB Antibody [NBP2-41319] - Analysis of PDIA1 in rat small intestine tissue lysate with PDIA1 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: Protein Disulfide Isomerase/P4HB Antibody - BSA Free [NBP2-41319]

Immunocytochemistry/ Immunofluorescence: Protein Disulfide Isomerase/P4HB Antibody - BSA Free [NBP2-41319]

Immunocytochemistry/Immunofluorescence: Protein Disulfide Isomerase/P4HB Antibody [NBP2-41319] - Immunofluorescence of Protein Disulfide Isomerase/P4HB in rat small intestine tissue with Protein Disulfide Isomerase/P4HB antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Protein Disulfide Isomerase/P4HB Antibody - BSA Free [NBP2-41319]

Immunohistochemistry-Paraffin: Protein Disulfide Isomerase/P4HB Antibody - BSA Free [NBP2-41319]

Immunohistochemistry-Paraffin: Protein Disulfide Isomerase/P4HB Antibody [NBP2-41319] - Rat small intestine tissue at 5 ug/ml.

Applications for Protein Disulfide Isomerase/P4HB Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Protein Disulfide Isomerase/P4HB

P4HB, the beta subunit of prolyl 4-hydroxylase, a highly abundant member of the PDI family. P4HB is a multifunctional enzyme, involved in hydroxylation of prolyl residues in preprocollagen, as well as continual rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Long Name

Proline 4-Hydroxylase, Beta Polypeptide

Alternate Names

DSI, ERBA2L, GIT, PDI, PDIA1, PO4DB, PO4HB, PROHB, Thbp

Gene Symbol

P4HB

Additional Protein Disulfide Isomerase/P4HB Products

Product Documents for Protein Disulfide Isomerase/P4HB Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Protein Disulfide Isomerase/P4HB Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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