Prox1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-18605

Novus Biologicals, part of Bio-Techne
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NBP1-18605
NBP1-18605-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

LYOPH mg/ml

View all Prox1 Antibodies »

Product Specifications

Immunogen

Recombinant human Prox-1

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 27122034).

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Prox1 Antibody

Western Blot: Prox1 Antibody [NBP1-18605]

Western Blot: Prox1 Antibody [NBP1-18605]

Western Blot: Prox1 Antibody [NBP1-18605] - Analysis with anti-human Prox-1
Immunocytochemistry/ Immunofluorescence: Prox1 Antibody [NBP1-18605]

Immunocytochemistry/ Immunofluorescence: Prox1 Antibody [NBP1-18605]

Immunocytochemistry/Immunofluorescence: Prox1 Antibody [NBP1-18605] - Cells expressing LLEC markers are present within embryonic mouse leptomeninges. As revealed by IHC, E12.5 mouse meninges (white bracket) contain cells that co-express LYVE1 (red), PROX1 (green), and MRC1 (white). DAPI marks the nuclei in blue (d). Scale?=?30 um. n?=?3 brains. E13.5 mouse meninges (white bracket) contain cells that co-express LYVE1 (red), PROX1 (green), and MRC1 (white). DAPI marks the nuclei in blue (h). Scale?=?30 um. n?=?3 brains. E18 mouse meninges (white bracket) contain cells that co-express LYVE1 (red), PROX1 (green), and MRC1 (white). PROX1 is cytoplasmic ( red arrows) in the meninges but nuclear in neurons ( blue arrows). DAPI marks the nuclei in blue. Image collected and cropped by CiteAb from the following publication (//link.springer.com/10.1007/s00401-019-02091-z) licensed under a CC-BY license.
Immunocytochemistry/ Immunofluorescence: Prox1 Antibody [NBP1-18605]

Immunocytochemistry/ Immunofluorescence: Prox1 Antibody [NBP1-18605]

Immunocytochemistry/Immunofluorescence: Prox1 Antibody [NBP1-18605] - PROX1 Antibody [NBP1-18605] - human skin stained with PROX1 (red), VEGFR3 (green) and TO-PRO (nuclei). ICC image submitted by a verified customer review.
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Applications for Prox1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:750 - 1:1000

Western Blot

1-5 ug/ml
Application Notes
Use in IHC-Frozen reported in scientific literature (PMID 27122034). Use in Immunohistochemistry-paraffin reported in scientific literature (PMID 31696318).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 3 using NBP1-18605 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. Please note the sample size of this product will be provided in reconstituted liquid form.

Formulation

0.5X PBS, pH 7.2

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Prox1

Prox1 is a prospero related homeobox gene. Its expression pattern suggests it has a role in a variety of embryonic tissues and may play a fundamental role in early development of the CNS. It may regulate gene expression and development of postmitotic undifferentiated young neurons. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.

Long Name

Prospero-related Homeobox 1

Alternate Names

Homeobox prospero-like protein PROX1, prospero homeobox 1, prospero homeobox protein 1, prospero-related homeobox 1, PROX-1

Entrez Gene IDs

5629 (Human)

Gene Symbol

PROX1

UniProt

Q92786

Additional Prox1 Products

Product Documents for Prox1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Prox1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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