PRPS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31654

Novus Biologicals, part of Bio-Techne
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NBP1-31654
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%), Rhesus Macaque (100%), Xenopus (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PRPS1 Antibodies »

Product Summary for PRPS1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human PRPS1. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (95%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRPS1 Antibody

Western Blot: PRPS1 Antibody [NBP1-31654]

Western Blot: PRPS1 Antibody [NBP1-31654]

Western Blot: PRPS1 Antibody [NBP1-31654] - Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: PRPS1 Antibody [NBP1-31654]

Immunocytochemistry/ Immunofluorescence: PRPS1 Antibody [NBP1-31654]

Immunocytochemistry/Immunofluorescence: PRPS1 Antibody [NBP1-31654] - Analysis of methanol-fixed HeLa, at 1:200 dilution.
Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP1-31654]

Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP1-31654]

Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP1-31654] - Paraffin-embedded SW480 xenograft, using antibody at 1:500 dilution.

Applications for PRPS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PRPS1

Phosphoribosylpyrophosphate synthetase (PRPS; EC 2.7.6.1) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine and pyrimidine biosynthesis (Roessler et al., 1990 [PubMed 2155397]). Three PRPS genes have been identified: the widely expressed PRPS1 and PRPS2 (MIM 311860) genes, which map to chromosome Xq22-q24 and Xp22, respectively, and PRPS3 (PRPS1L1; MIM 611566), which maps to chromosome 7 and appears to be transcribed only in testis (Becker, 2001).[supplied by OMIM]

Long Name

Phosphoribosyl Pyrophosphate Synthetase 1

Alternate Names

CMTX5, DFN2, DFNX1, PPRibP, PRS I, PRS-I, PRSI

Entrez Gene IDs

5631 (Human)

Gene Symbol

PRPS1

UniProt

P60891 (Human)

Additional PRPS1 Products

Product Documents for PRPS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PRPS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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