PSAP Antibody (D12)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41708

Novus Biologicals, part of Bio-Techne
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NBP3-41708
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # D12

Concentration

1 mg/ml

View all PSAP Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human PSAP (Uniprot#: P07602; Gly17-Asn524 (Uniprot#: P07602)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for PSAP Antibody (D12)

PSAP Antibody (D12)

Immunocytochemistry /Immunofluorescence: PSAP Antibody (D12) [NBP3-41708] -

Immunocytochemistry /Immunofluorescence: PSAP Antibody (D12) [NBP3-41708] - FITC staining on IF; Sample: Human HepG2 cell; Primary Ab: 30ug/ml NBP3-41708; Second Ab: 2ug/ml FITC-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Applications for PSAP Antibody (D12)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PSAP

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.

Long Name

Prosaposin

Alternate Names

GLBA, SAP1

Gene Symbol

PSAP

Additional PSAP Products

Product Documents for PSAP Antibody (D12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PSAP Antibody (D12)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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