PSAP Antibody (SR2219)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22242

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22242-100ul
NBP3-22242-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2219

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PSAP Antibodies »

Product Summary for PSAP Antibody (SR2219)

Immunogen

A synthesized peptide derived from human PSAP (Uniprot #: P07602)

Specificity

Detects endogenous levels of total PSAP

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PSAP Antibody (SR2219)

Western Blot: PSAP Antibody (SR2219) [NBP3-22242] -

Western Blot: PSAP Antibody (SR2219) [NBP3-22242] - Western blot analysis using NBP3-22242 in HepG2 cell lysate.

Applications for PSAP Antibody (SR2219)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:1000-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PSAP

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.

Long Name

Prosaposin

Alternate Names

GLBA, SAP1

Gene Symbol

PSAP

Additional PSAP Products

Product Documents for PSAP Antibody (SR2219)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PSAP Antibody (SR2219)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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