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PSF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-38597

Novus Biologicals, part of Bio-Techne
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NBP3-38597-100ul
NBP3-38597-20ul

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human PSF2 (NP_057179.1).

Sequence:
MDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDLGPFNPGLPVEVPLWLAINLKQRQKCRLLPPEWMDVEKLEKMRDHERKEETFTPMPSPYYMELTKLLLNHASDNIPKADEIRTLVKDMWDTRIAKLRVSADSFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYKLRTNLQPLESTQSQDF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PSF2 Antibody

PSF2 Antibody

Western Blot: PSF2 Antibody [NBP3-38597] -

Western Blot: PSF2 Antibody [NBP3-38597] - Western blot analysis of various lysates using PSF2 Rabbit pAb at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

Applications for PSF2 Antibody

Application
Recommended Usage

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PSF2

PSF2, also known as DNA replication complex GINS protein PSF2, is a 185 amino acid protein that is 21 kDa, belongs to the GINS2/PSF2 family, localizes in the nucleus, plays an essential role in the initiation of DNA replication and progression of DNA replication forks, and seems to bind preferentially to single-stranded DNA. This protein is being studied for its involvement in breast cancer. The protein has been also linked to the unwinding of DNA, S Phase, DNA strand elongation, synthesis of DNA, DNA replication, cell cycle, and cell cycle, mitotic pathways where it interacts with CHEK2, GINS4, FANCF, GTF2A1L, KPNA4, LMNB1, and other proteins.

Alternate Names

DNA replication complex GINS protein PSF2, GINS complex subunit 2, GINS complex subunit 2 (Psf2 homolog), HSPC037, PSF2Pfs2

Gene Symbol

GINS2

Additional PSF2 Products

Product Documents for PSF2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PSF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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