PSMC3 Antibody (OTI9F3) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-73696B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-02316

Alexa Fluor 350

NBP2-73696AF350

Alexa Fluor 405

NBP2-73696AF405

Alexa Fluor 488

NBP2-73696AF488

Alexa Fluor 532

NBP2-73696AF532

Alexa Fluor 594

NBP2-73696AF594

Alexa Fluor 647

NBP2-73696AF647

Alexa Fluor 700

NBP2-73696AF700

Alexa Fluor 750

NBP2-73696AF750

Allophycocyanin

NBP2-73696APC

CoraFluor 1

NBP2-73696CL1

DyLight 350

NBP2-73696UV

DyLight 405

NBP2-73696V

DyLight 488

NBP2-73696G

DyLight 550

NBP2-73696R

DyLight 594

NBP2-73696DL594

DyLight 650

NBP2-73696C

DyLight 680

NBP2-73696FR

DyLight 755

NBP2-73696IR

FITC

NBP2-73696F

HRP

NBP2-73696H

Janelia Fluor 525

NBP2-73696JF525

Janelia Fluor 549

NBP2-73696JF549

Janelia Fluor 585

NBP2-73696JF585

Janelia Fluor 635

NBP2-73696JF635

Janelia Fluor 646

NBP2-73696JF646

Janelia Fluor 669

NBP2-73696JF669

mFluor Violet 450 SE

NBP2-73696MFV450

mFluor Violet 500 SE

NBP2-73696MFV500

mFluor Violet 610 SE

NBP2-73696MFV610

PE

NBP2-73696PE

PerCP

NBP2-73696PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-73696

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Canine

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ Clone # OTI9F3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PSMC3 Antibodies »

Product Specifications

Immunogen

Full length recombinant protein of human PSMC3 (NP_002795) produced in HEK293T cells.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for PSMC3 Antibody (OTI9F3) [Biotin]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PSMC3

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq]

Alternate Names

human immunodeficiency virus tat transactivator binding protein-1, MGC8487, proteasome (prosome, macropain) 26S subunit, ATPase, 3,26S proteasome AAA-ATPase subunit RPT5, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, TBP-126S protease regulatory subunit 6A, TBP1Tat-binding protein 1

Gene Symbol

PSMC3

Additional PSMC3 Products

Product Documents for PSMC3 Antibody (OTI9F3) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PSMC3 Antibody (OTI9F3) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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