PSMC6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29490

Novus Biologicals, part of Bio-Techne
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NBP3-29490
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PSMC6 Antibodies »

Product Specifications

Immunogen

between 275 and 325

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PSMC6 Antibody

PSMC6 Antibody

Immunoprecipitation:PSMC6 AntibodyNBP3-29490] -

Immunoprecipitation:PSMC6 AntibodyNBP3-29490] -Detection of human PSMC6 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-PSMC6 antibody NBP3-29490 used for IP at 6 µg/mg lysate. PSMC6 was also immunoprecipitated by rabbit anti-PSMC6., which recognizes a downstream epitope. For blotting immunoprecipitated PSMC6, was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for PSMC6 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PSMC6

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Alternate Names

26S protease regulatory subunit 10B, 26S protease regulatory subunit S10B, 26S proteasome AAA-ATPase subunit RPT4, CADP44, conserved ATPase domain protein 44, MGC12520, p42, P44, proteasome (prosome, macropain) 26S subunit, ATPase, 6, Proteasome 26S subunit ATPase 6, Proteasome subunit p42, SUG2

Gene Symbol

PSMC6

Additional PSMC6 Products

Product Documents for PSMC6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PSMC6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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