PTP alpha/PTPRA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-62456

Novus Biologicals, part of Bio-Techne
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NBP1-62456
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all PTP alpha/PTPRA Antibodies »

Product Summary for PTP alpha/PTPRA Antibody

Immunogen

Synthetic peptides corresponding to PTPRA(protein tyrosine phosphatase, receptor type, A) The peptide sequence was selected from the C terminal of PTPRA. Peptide sequence SRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

89 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PTP alpha/PTPRA Antibody

Western Blot: PTP alpha/PTPRA Antibody [NBP1-62456]

Western Blot: PTP alpha/PTPRA Antibody [NBP1-62456]

Western Blot: PTP alpha/PTPRA Antibody [NBP1-62456] - 293T cells lysate, concentration 0.2-1 ug/ml.

Applications for PTP alpha/PTPRA Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTP alpha/PTPRA

PTPRA is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRA contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. PTPRA has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Long Name

Protein Tyrosine Phosphatase Receptor-type alpha

Alternate Names

HEPTP, HLPR, LRP, PTPase-alpha, PTPRA, PTPRL2

Gene Symbol

PTPRA

UniProt

P18433 (Human)

Additional PTP alpha/PTPRA Products

Product Documents for PTP alpha/PTPRA Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PTP alpha/PTPRA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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