PTP mu/PTPRM Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14456

Novus Biologicals, part of Bio-Techne
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NBP3-14456
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bat (100%), Bovine (100%), Equine (100%), Hamster (100%), Monkey (100%), Mouse (100%), Opossum (94%), Orangutan (100%), Primate (100%), Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all PTP mu/PTPRM Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from internal region of human PTP mu/PTPRM.

Epitope

Internal

Reactivity Notes

Expected reactivity based on percent sequence identity: Canine (88%), Gorilla, Xenopus (81%)

Specificity

Human PTP mu/PTPRM. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PTP mu/PTPRM Antibody

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody [NBP3-14456]

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody [NBP3-14456]

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody [NBP3-14456] - Immunohistochemistry of formalin-fixed, paraffin-embedded human retina after heat-induced antigen retrieval.

Applications for PTP mu/PTPRM Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PTP mu/PTPRM

PTPRM is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Long Name

Protein Tyrosine Phosphatase Receptor-type M

Alternate Names

PTPRL1, PTPRM, R-PTP-mu

Gene Symbol

PTPRM

Additional PTP mu/PTPRM Products

Product Documents for PTP mu/PTPRM Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTP mu/PTPRM Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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