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PTRF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60634

Novus Biologicals, part of Bio-Techne
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NB100-60634

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 150 and 200 of human RNA polymerase I and transcript release factor using the numbering given in entry NP_036364.2 (GeneID 284119).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTRF Antibody

Immunoprecipitation: PTRF Antibody [NB100-60634]

Immunoprecipitation: PTRF Antibody [NB100-60634]

Immunoprecipitation: PTRF Antibody [NB100-60634] - Detection of Human PTRF by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PTRF antibody NB100-60634 used for IP at 3 mcg/mg lysate. PTRF was also immunoprecipitated by rabbit anti-PTRF antibodies NB100-60633 and NB100-60635, which recognize other epitopes. Detection: Chemiluminescence with exposure times of 3 seconds (A and B).

Applications for PTRF Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 5 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PTRF

PTRF (polymerase I and transcript release factor) was first identified as a TTF-I and RNA polymerase I (RNA Pol I) interacting protein that functions in the termination of RNA polymerase I transcription. PTRF has also been described as a protein that localizes to the plasma membrane and caveolae of adipocytes and whose localization is under the control of insulin. In this context, PTRF has been observed to associate with a lipase and have an extranuclear role in the regulation of lipolysis. PTRF is also known as FKSG13.

Alternate Names

CAVIN, Cavin-1, CGL4, FLJ90031, polymerase I and transcript release factor, RNA polymerase I and transcript release factor, TTF-I interacting peptide 12

Entrez Gene IDs

284119 (Human)

Gene Symbol

CAVIN1

Additional PTRF Products

Product Documents for PTRF Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTRF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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