QDPR Antibody (M1)

Novus Biologicals, part of Bio-Techne | Catalog # H00005860-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Knockdown Validated, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # M1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all QDPR Antibodies »

Product Specifications

Immunogen

QDPR (AAH00576, 1 a.a. ~ 244 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQADQVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTELTPAYF

Specificity

QDPR - quinoid dihydropteridine reductase

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for QDPR Antibody (M1)

Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02] - Analysis of QDPR expression in transfected 293T cell line by QDPR monoclonal antibody (M02), clone M1.Lane 1: QDPR transfected lysate(25.8 KDa).Lane 2: Non-transfected lysate.
Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02] - Analysis of QDPR over-expressed 293 cell line, cotransfected with QDPR Validated Chimera RNAi ( Cat # H00005860-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with QDPR monoclonal antibody (M02), clone M1 (Cat # H00005860-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02]

Western Blot: QDPR Antibody (M1) [H00005860-M02] - QDPR monoclonal antibody (M02), clone M1 Analysis of QDPR expression in HL-60.
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Applications for QDPR Antibody (M1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has been used for RNAi Validation and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: QDPR

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Long Name

Quinoid Dihydropteridine Reductase

Alternate Names

DHPR, HDHPR, PKU2, SDR33C1

Entrez Gene IDs

5860 (Human)

Gene Symbol

QDPR

OMIM

261630 (Human)

UniProt

AAH00576 (Human)

Additional QDPR Products

Product Documents for QDPR Antibody (M1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for QDPR Antibody (M1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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