Rab11A Antibody (SR1380)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21656

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21656-100ul
NBP3-21656-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1380

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Rab11A Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Rab11A (Uniprot #: P62491)

Specificity

Detects endogenous levels of total Rab11A

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Rab11A Antibody (SR1380)

Western Blot: Rab11A Antibody (SR1380) [NBP3-21656] -

Western Blot: Rab11A Antibody (SR1380) [NBP3-21656] - Western blot analysis using NBP3-21656 in HeLa cell lysate.

Applications for Rab11A Antibody (SR1380)

Application
Recommended Usage

Immunoprecipitation

1:30

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rab11A

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There are over 40 Rab proteins in mammals. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane. Rab11a is ubiquitously expressed, while Rab11b is expressed mainly in the heart and brain.

Long Name

RAs Genes from Brain Protein 11A

Alternate Names

Rab-11, YL8

Gene Symbol

RAB11A

Additional Rab11A Products

Product Documents for Rab11A Antibody (SR1380)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Rab11A Antibody (SR1380)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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