Rab11A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3612

Novus Biologicals, part of Bio-Techne
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NB120-3612
NB120-3612-50ug
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Key Product Details

Species Reactivity

Human, Porcine, Canine, Primate

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Rab11A Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues M(1) G T R D D E Y D Y L F K V V L I C(17) of human Rab11.

Reactivity Notes

Expected cross-reactivity with Rat and Mouse base on sequence identity.

Localization

Located on the cytoplasmic face of organelles and vesicles.

Specificity

NB120-3612 detects Rab 11 from human and non-human primate samples.

Marker

Recycling Endosome Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rab11A Antibody

Western Blot: Rab11A Antibody [NB120-3612]

Western Blot: Rab11A Antibody [NB120-3612]

Western Blot: Rab11A Antibody [NB120-3612] - Analysis of PC3 cell extract.

Applications for Rab11A Antibody

Application
Recommended Usage

Western Blot

6.6 ug/ml
Application Notes
WB: Detects an approx. 22 kDa protein representing Rab 11 in CV1, PC3, and HeLa cell extract. Another less prominent, unknown band is also detected by this antibody at approx. 35 kDa.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Rab11A

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.

Long Name

RAs Genes from Brain Protein 11A

Alternate Names

Rab-11, YL8

Entrez Gene IDs

8766 (Human)

Gene Symbol

RAB11A

Additional Rab11A Products

Product Documents for Rab11A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Rab11A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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