RAC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33449

Novus Biologicals, part of Bio-Techne
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NBP1-33449
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Chicken (99%), Drosophila (92%), Rat (99%), Rhesus Macaque (100%), Xenopus (96%), Zebrafish (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RAC2 Antibodies »

Product Summary for RAC2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human RAC2. The exact sequence is proprietary.

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RAC2 Antibody

Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449]

Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449]

Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449] - Mouse fore brain. RAC2 antibody [N1C3] dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449]

Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449]

Immunohistochemistry-Paraffin: RAC2 Antibody [NBP1-33449] - NCI-N87 xenograft, using RAC2 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
RAC2 Antibody

Immunocytochemistry/ Immunofluorescence: RAC2 Antibody [NBP1-33449] -

Immunocytochemistry/ Immunofluorescence: RAC2 Antibody [NBP1-33449] - RAC2 antibody [N1C3] detects RAC2 protein at cell membrane and cytoplasm by immunofluorescent analysis.
Sample: MOLT-4 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: RAC2 stained by RAC2 antibody [N1C3] (NBP1-33449) diluted at 1:500.
Blue: Fluoroshield with DAPI .
View 2 more images

Applications for RAC2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RAC2

RAC2 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, RAC2 binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. There are two isoforms of RAC2; isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.

Alternate Names

GX, HSPC022, ras-related C3 botulinum toxin substrate 2 (rho family, small GTP bindingprotein Rac2), rho family, small GTP binding protein Rac2, small GTP-bindingprotein Rac2)

Gene Symbol

RAC2

Additional RAC2 Products

Product Documents for RAC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RAC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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