Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (93%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all RANBP10 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the center of human RANBP10. The immunogen is located within amino acids 380 - 430 of RANBP10. Amino Acid Squence: VASTSKQNHSKYPA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RANBP10 Antibody - BSA Free

Western Blot: RANBP10 AntibodyBSA Free [NBP1-77372]

Western Blot: RANBP10 AntibodyBSA Free [NBP1-77372]

Western Blot: RANBP10 Antibody [NBP1-77372] - Human skeletal muscle tissue lysate with RANBP10 antibody at (A) 1 and (B) 2 ug/mL.
RANBP10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: RANBP10 Antibody - BSA Free [NBP1-77372] -

Immunocytochemistry/ Immunofluorescence: RANBP10 Antibody - BSA Free [NBP1-77372] - Immunofluorescence of RANBP10 in mouse skeletal muscle tissue with RANBP10 antibody at 20 u/mL.
RANBP10 Antibody - BSA Free

Immunohistochemistry: RANBP10 Antibody - BSA Free [NBP1-77372] -

Immunohistochemistry: RANBP10 Antibody - BSA Free [NBP1-77372] - Immunohistochemistry of RANBP10 in human skeletal muscle tissue with RANBP10 antibody at 5 ug/mL.

Applications for RANBP10 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RANBP10

The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.

Alternate Names

KIAA1464FLJ31165, RAN binding protein 10, ran-binding protein 10, RanBP10

Gene Symbol

RANBP10

UniProt

EAW83167 (Human)

Additional RANBP10 Products

Product Documents for RANBP10 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RANBP10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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