RanBP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-2938

Novus Biologicals, part of Bio-Techne
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NB120-2938
NB120-2938-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Bovine

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all RanBP2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.

Localization

Nuclear

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RanBP2 Antibody

Western Blot: RanBP2 Antibody [NB120-2938]

Western Blot: RanBP2 Antibody [NB120-2938]

Western Blot: RanBP2 Antibody [NB120-2938] - Effect of hypoxia on the interaction between HIF1alpha and BICD1. Co-immunoprecipitation of HIF1alpha, Dynein IC, Importin alpha3, RanBP2 with IgG and BICD1 antibodies were shown in left panel. Total protein expressions in lysate were shown in right panel. n = 3. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41418-018-0241-1) licensed under a CC-BY license.
Immunohistochemistry: RanBP2 Antibody [NB120-2938]

Immunohistochemistry: RanBP2 Antibody [NB120-2938]

Immunohistochemistry: RanBP2 Antibody [NB120-2938] - Figure 1 illustrates immunohistochemical staining of RanBP2 in bovine retina using NB120-2938. Figure 2 illustrates Western blot detection of RanBP2 from human retinal extracts using NB120-2938.
Western Blot: RanBP2 Antibody [NB120-2938]

Western Blot: RanBP2 Antibody [NB120-2938]

Western Blot: RanBP2 Antibody [NB120-2938] - Analysis of human retinal extracts.

Applications for RanBP2 Antibody

Application
Recommended Usage

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

1:10 - 1:500

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RanBP2

Transport of macromolecules into and out of the nucleus occurs through nuclear pore complexes (NPC). This energy-dependent process involves nucleoporins at the NPC, associated transport proteins and GTP. The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane.

Alternate Names

ANE1, E3 SUMO-protein ligase RanBP2, EC 5.2.1.8, Nuclear pore complex protein Nup358, nucleoporin 358, Nucleoporin Nup358, NUP358TRP2, p270, RAN binding protein 2, Ran-binding protein 2, RanBP2, transformation-related protein 2,358 kDa nucleoporin, TRP1

Entrez Gene IDs

5903 (Human); 785768 (Bovine)

Gene Symbol

RANBP2

UniProt

P49792 (Human)

Additional RanBP2 Products

Product Documents for RanBP2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RanBP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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