Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all RASD2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human TEM2. The immunogen is located within amino acids 20 - 70 of TEM2. Amino Acid Squence: FLNGRFEDQYTPTIED

Specificity

TEM2 antibody may cross-react with the closely related protein RASD1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RASD2 Antibody - BSA Free

Western Blot: RASD2 AntibodyBSA Free [NBP1-77313]

Western Blot: RASD2 AntibodyBSA Free [NBP1-77313]

Western Blot: RASD2 Antibody [NBP1-77313] - Rat colon tissue lysate with RASD2 antibody at (A) 1 and (B) 2 ug/ml.
RASD2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: RASD2 Antibody - BSA Free [NBP1-77313] -

Immunocytochemistry/ Immunofluorescence: RASD2 Antibody - BSA Free [NBP1-77313] - Immunofluorescence of RASD2 in Human Colon cells with RASD2 antibody at 20 u/mL.
RASD2 Antibody - BSA Free

Immunohistochemistry: RASD2 Antibody - BSA Free [NBP1-77313] -

Immunohistochemistry: RASD2 Antibody - BSA Free [NBP1-77313] - Immunohistochemistry of RASD2 in human colon tissue with RASD2 antibody at 2.5 u/mL.

Applications for RASD2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RASD2

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. TEM2 antibody may cross-react with the closely related protein RASD1.

Alternate Names

GTP-binding protein Rhes, MGC:4834, RASD family, member 2, Rhes, TEM2Ras homolog enriched in striatum, Tumor endothelial marker 2

Gene Symbol

RASD2

UniProt

Q96D21 (Human)

Additional RASD2 Products

Product Documents for RASD2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RASD2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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