Rat CCR2 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB8368A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Rat
Cited:
Rat
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2B Clone # 890231
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with rat CCR2
Accession # O55193
Accession # O55193
Specificity
Stains rat CCR2 transfectants but not irrelevant transfectants in flow cytometry.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Rat CCR2 APC-conjugated Antibody
Detection of CCR2 in HEK293 Human Cell Line Transfected with Rat CCR2 and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with rat CCR2 and eGFP was stained with either (A) Mouse Anti-Rat CCR2 APC-conjugated Monoclonal Antibody (Catalog # FAB8368A) or (B) Mouse IgG2BAllophycocyanin Isotype Control (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.Applications for Rat CCR2 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
0.25-1 µg/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with rat CCR2 and eGFP
Sample: HEK293 human embryonic kidney cell line transfected with rat CCR2 and eGFP
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CCR2
CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Two alternate splice forms (CCR2A and CCR2B) differ only by the addition of 14 amino acids to the intracellular carboxyl terminal. Rat CCR2 shares 95% aa sequence identity with mouse CCR2.
Alternate Names
CC-CKR-2, CCR2, CCR2B, CD192, CKR2, CKR2A, CMKBR2, FLJ78302, MCP-1-R
Gene Symbol
CCR2
UniProt
Additional CCR2 Products
Product Documents for Rat CCR2 APC-conjugated Antibody
Product Specific Notices for Rat CCR2 APC-conjugated Antibody
For research use only
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