RbAp46 Antibody (2A10C2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27151

Novus Biologicals, part of Bio-Techne
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NBP3-27151-0.025ml
NBP3-27151-0.1ml
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2A10C2

Concentration

1 mg/ml

View all RbAp46 Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human RbAp46 (AA: 1-200) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

47.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RbAp46 Antibody (2A10C2)

Immunohistochemistry: RbAp46 Antibody (2A10C2) [NBP3-27151] -

Immunohistochemistry: RbAp46 Antibody (2A10C2) [NBP3-27151] - Analysis of paraffin-embedded rectum cancer tissues using RbAp46 mouse mAb with DAB staining.

Western Blot: RbAp46 Antibody (2A10C2) [NBP3-27151] -

Western Blot: RbAp46 Antibody (2A10C2) [NBP3-27151] - Analysis using RbAp46 mAb against HEK293 (1) and RbAp46 (AA: 1-200)-hIgGFc transfected HEK293 (2) cell lysate.

ELISA: RbAp46 Antibody (2A10C2) [NBP3-27151] -

ELISA: RbAp46 Antibody (2A10C2) [NBP3-27151] - Black line: Control Antigen (100 ng); Purple line: Antigen (10 ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Applications for RbAp46 Antibody (2A10C2)

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Immunocytochemistry/ Immunofluorescence

1:200 - 1:1000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RbAp46

RBBP7 antibody, also known as RbAp46 (Retinoblastoma protein associated protein 46), is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex, as are the histone deacetylase proteins (HDACs). It shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RBBP7 has also been demonstrated to be up-regulated by the Wilms' tumor suppressor gene product, WT1. In addition, cells transfected with this antibody have shown strong inhibition of growth.

Alternate Names

G1/S transition control protein-binding protein RbAp46, Histone acetyltransferase type B subunit 2, histone-binding protein RBBP7, MGC138867, Nucleosome-remodeling factor subunit RBAP46, RBAP46, RBBP-7, retinoblastoma binding protein 7, Retinoblastoma-binding protein 7MGC138868, Retinoblastoma-binding protein p46, retinoblastoma-binding protein RbAp46

Gene Symbol

RBBP7

Additional RbAp46 Products

Product Documents for RbAp46 Antibody (2A10C2)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RbAp46 Antibody (2A10C2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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