RBM8A Antibody (5K5E6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15805

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15805-100ul
NBP3-15805-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 5K5E6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RBM8A Antibodies »

Product Summary for RBM8A Antibody (5K5E6)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RBM8A (Q9Y5S9). MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIK

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RBM8A Antibody (5K5E6)

Western Blot: RBM8A Antibody (5K5E6) [NBP3-15805]

Western Blot: RBM8A Antibody (5K5E6) [NBP3-15805]

Western Blot: RBM8A Antibody (5K5E6) [NBP3-15805] - Western blot analysis of extracts of various cell lines, using RBM8A Rabbit mAb (NBP3-15805) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.

Applications for RBM8A Antibody (5K5E6)

Application
Recommended Usage

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RBM8A

Pre-mRNA splicing appears to play an important role in regulation of gene expression. It has been shown in a number of studies that during the splicing process, specific proteins are recruited to the mRNA and assemble into a complex of mRNA-protein near the exon-exon junction. This complex is termed mRNA-protein complex (mRNP), or the exon-exon junction complex. Several proteins were found to be present in this complex including Y14, magoh, Aly/REF, RNPS1, Upf3, and DEK. Y14 is a 174 amino acid RNA-binding protein that contains one RNA-binding domain in the middle of the protein. Y14 binds to the spliced mRNAs in the nucleus and is exported with the mRNA to the cytoplasm. Similar to other proteins in the mRNA-protein complex, Y14 can interact with the mRNA export factor TAP and enhance the export of the mRNAs. Y14 binds to different mRNAs approx.

Alternate Names

Binder of OVCA1-1, BOV-1, BOV-1A, BOV-1B, BOV-1C, MDS014, RBM8BRBM8, ribonucleoprotein RBM8, Ribonucleoprotein RBM8A, RNA binding motif protein 8A, RNA binding motif protein 8B, RNA-binding motif protein 8A, RNA-binding protein 8A, RNA-binding protein Y14, Y14, ZNRP, ZRNP1

Gene Symbol

RBM8A

Additional RBM8A Products

Product Documents for RBM8A Antibody (5K5E6)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RBM8A Antibody (5K5E6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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