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RBM8A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13019

Novus Biologicals, part of Bio-Techne
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NBP3-13019

Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Bovine (98%), Mouse (100%), Xenopus (93%), Zebrafish (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for RBM8A Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human RBM8A. The exact sequence is proprietary.

Reactivity Notes

Japanese Medaka (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for RBM8A Antibody

Western Blot: RBM8A Antibody [NBP3-13019]

Western Blot: RBM8A Antibody [NBP3-13019]

Western Blot: RBM8A Antibody [NBP3-13019] - Various whole cell extracts (30 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with RBM8A antibody (NBP3-13019) diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: RBM8A Antibody [NBP3-13019]

Immunocytochemistry/ Immunofluorescence: RBM8A Antibody [NBP3-13019]

Immunocytochemistry/Immunofluorescence: RBM8A Antibody [NBP3-13019] - RBM8A antibody detects RBM8A protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RBM8A protein stained by RBM8A antibody (NBP3-13019) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunohistochemistry-Paraffin: RBM8A Antibody [NBP3-13019]

Immunohistochemistry-Paraffin: RBM8A Antibody [NBP3-13019]

Immunohistochemistry-Paraffin: RBM8A Antibody [NBP3-13019] - RBM8A antibody detects RBM8A protein at cytoplasm and nucleus in rat adrenal gland by immunohistochemical analysis. Sample: Paraffin-embedded rat adrenal gland. RBM8A antibody (NBP3-13019) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for RBM8A Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RBM8A

Pre-mRNA splicing appears to play an important role in regulation of gene expression. It has been shown in a number of studies that during the splicing process, specific proteins are recruited to the mRNA and assemble into a complex of mRNA-protein near the exon-exon junction. This complex is termed mRNA-protein complex (mRNP), or the exon-exon junction complex. Several proteins were found to be present in this complex including Y14, magoh, Aly/REF, RNPS1, Upf3, and DEK. Y14 is a 174 amino acid RNA-binding protein that contains one RNA-binding domain in the middle of the protein. Y14 binds to the spliced mRNAs in the nucleus and is exported with the mRNA to the cytoplasm. Similar to other proteins in the mRNA-protein complex, Y14 can interact with the mRNA export factor TAP and enhance the export of the mRNAs. Y14 binds to different mRNAs approx.

Alternate Names

Binder of OVCA1-1, BOV-1, BOV-1A, BOV-1B, BOV-1C, MDS014, RBM8BRBM8, ribonucleoprotein RBM8, Ribonucleoprotein RBM8A, RNA binding motif protein 8A, RNA binding motif protein 8B, RNA-binding motif protein 8A, RNA-binding protein 8A, RNA-binding protein Y14, Y14, ZNRP, ZRNP1

Gene Symbol

RBM8A

Additional RBM8A Products

Product Documents for RBM8A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RBM8A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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