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RCOR1/CoREST Antibody (SR2107)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21977

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21977-100ul
NBP3-21977-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2107

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for RCOR1/CoREST Antibody (SR2107)

Immunogen

A synthesized peptide derived from human RCOR1/CoREST (Uniprot #: Q9UKL0)

Specificity

Detects endogenous levels of total RCOR1/CoREST

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RCOR1/CoREST Antibody (SR2107)

Western Blot: RCOR1/CoREST Antibody (SR2107) [NBP3-21977] -

Western Blot: RCOR1/CoREST Antibody (SR2107) [NBP3-21977] - Western blot analysis using NBP3-21977 in Molt-4 cell lysate.

Applications for RCOR1/CoREST Antibody (SR2107)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:1000-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RCOR1/CoREST

Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1).

Long Name

REST Corepressor 1

Alternate Names

CoREST, RCOR1

Gene Symbol

RCOR1

Additional RCOR1/CoREST Products

Product Documents for RCOR1/CoREST Antibody (SR2107)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RCOR1/CoREST Antibody (SR2107)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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