Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all RIMS3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Rim3. The immunogen is located within amino acids 60 - 110 of Rim3. Amino Acid Squence: LPQPEGATKKLRSNIRR

Specificity

This antibody is predicted to have no cross-reactivity to other Rim proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RIMS3 Antibody - BSA Free

Western Blot: RIMS3 AntibodyBSA Free [NBP1-76874]

Western Blot: RIMS3 AntibodyBSA Free [NBP1-76874]

Western Blot: RIMS3 Antibody [NBP1-76874] - Human brain tissue lysate with Rims3 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.
RIMS3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: RIMS3 Antibody - BSA Free [NBP1-76874] -

Immunocytochemistry/ Immunofluorescence: RIMS3 Antibody - BSA Free [NBP1-76874] - Immunofluorescence of rim3 in human brain tissue with rim3 antibody at 5 ug/mL.
RIMS3 Antibody - BSA Free

Immunohistochemistry: RIMS3 Antibody - BSA Free [NBP1-76874] -

Immunohistochemistry: RIMS3 Antibody - BSA Free [NBP1-76874] - Immunohistochemistry of RIMS3 in human brain tissue with RIMS3 antibody at 2.5 ug/mL.

Applications for RIMS3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RIMS3

Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity. This antibody is predicted to have no cross-reactivity to other Rim proteins.

Alternate Names

KIAA0137, KIAA0237, Nim3, NIM3Rab-3 interacting molecule 3, Rab-3-interacting molecule 3, regulating synaptic membrane exocytosis 3, regulating synaptic membrane exocytosis protein 3, RIM 3, RIM3, RIM3 gamma

Gene Symbol

RIMS3

UniProt

NP_055562 (Human)

Additional RIMS3 Products

Product Documents for RIMS3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RIMS3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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