RNAscope™ Antibody Human CD8 Oligo-C4
Advanced Cell Diagnostics, part of Bio-Techne | Catalog # 322951
For use only with the RNAscope™ Multiomic Kits
Key Product Details
Species Reactivity
Human
Applications
RNAscope Multiomic
Label
RNAscope C4 Oligo
Antibody Source
Monoclonal Mouse IgG1 Clone # C8/144B
Product Specifications
Immunogen
Human CD8 alpha chain. 13 amino acid peptide from C-terminal cytoplasmic domain.
Specificity
Detects human CD8a in RNAscope assays.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for RNAscope™ Antibody Human CD8 Oligo-C4
Application
Recommended Usage
RNAscope Multiomic
1:75 dilution
Formulation, Preparation, and Storage
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: CD8
CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.
Alternate Names
CD8, CD8A
Entrez Gene IDs
Gene Symbol
CD8A
Additional CD8 Products
Product Specific Notices for RNAscope™ Antibody Human CD8 Oligo-C4
For research use only
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