ROBLD3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87951

Novus Biologicals, part of Bio-Techne
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NBP1-87951
NBP1-87951-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ROBLD3 Antibodies »

Product Summary for ROBLD3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ROBLD3 Antibody

Immunocytochemistry/ Immunofluorescence: ROBLD3 Antibody [NBP1-87951]

Immunocytochemistry/ Immunofluorescence: ROBLD3 Antibody [NBP1-87951]

Immunocytochemistry/Immunofluorescence: ROBLD3 Antibody [NBP1-87951] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.
Immunohistochemistry-Paraffin: ROBLD3 Antibody [NBP1-87951]

Immunohistochemistry-Paraffin: ROBLD3 Antibody [NBP1-87951]

Immunohistochemistry-Paraffin: ROBLD3 Antibody [NBP1-87951] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Applications for ROBLD3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ROBLD3

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Alternate Names

ENDAP, Endosomal adaptor protein p14, HSPC003, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, Late endosomal/lysosomal Mp1-interacting protein, MAPBPIPRoadblock domain-containing protein 3, MAPKSP1 adaptor protein, MAPKSP1AP, Mitogen-activated protein-binding protein-interacting protein, mitogen-activated protein-binding protein-interacting protein (MAPBPIP), p14Ragulator2, roadblock domain containing 3, ROBLD3

Gene Symbol

LAMTOR2

Additional ROBLD3 Products

Product Documents for ROBLD3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ROBLD3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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