ROR beta Antibody (SR1948)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22118

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22118-100ul
NBP3-22118-50ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1948

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ROR beta/NR1F2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human ROR beta (Uniprot #: Q92753)

Specificity

Detects endogenous levels of total ROR beta

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ROR beta Antibody (SR1948)

Western Blot: ROR beta Antibody (SR1948) [NBP3-22118] -

Western Blot: ROR beta Antibody (SR1948) [NBP3-22118] - Western blot analysis using NBP3-22118 in HepG2 cell lysate.

Applications for ROR beta Antibody (SR1948)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ROR beta/NR1F2

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain. ESTs have been isolated from human tissue libraries, including cancerous human kidney and normal brain, pineal and eye.

Long Name

Retinoic Acid-Related Orphan Receptor beta

Alternate Names

NR1F2, RORB, RZRB

Gene Symbol

RORB

Additional ROR beta/NR1F2 Products

Product Documents for ROR beta Antibody (SR1948)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ROR beta Antibody (SR1948)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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