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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI1A1

Concentration

1 mg/ml

Product Summary for ROS Antibody (OTI1A1)

Immunogen

Human recombinant protein fragment corresponding to amino acids 1882-2125 of human ROS1(NP_002935) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for ROS Antibody (OTI1A1)

Western Blot: ROS Antibody (OTI1A1) [NBP2-45627]

Western Blot: ROS Antibody (OTI1A1) [NBP2-45627]

Western Blot: ROS Antibody (OTI1A1) [NBP2-45627] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS.
Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627]

Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627]

Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627] - Staining of paraffin-embedded HCC78 (left) and HeLa (right) xenograft using TA805804 (0.2ug/ml). (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3min).
Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627]

Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627]

Immunohistochemistry-Paraffin: ROS Antibody (OTI1A1) [NBP2-45627] - Staining of HCC78 cells using anti-ROS1 mouse monoclonal antibody (Left). The right is HELA cells as negative control.

Applications for ROS Antibody (OTI1A1)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5000-10000

Immunohistochemistry

1:500

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ROS1

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. (provided by RefSeq)

Long Name

ROS Proto-Oncogene 1, Receptor Tyrosine Kinase

Alternate Names

c-Ros-1, MCF3

Gene Symbol

ROS1

Additional ROS1 Products

Product Documents for ROS Antibody (OTI1A1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ROS Antibody (OTI1A1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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