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ROS Antibody (PD01-27)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32917

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-32917

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # PD01-27

Concentration

1 mg/ml

Product Summary for ROS Antibody (PD01-27)

Immunogen

Synthetic peptide within Human ROS aa 2050-2150. (Uniprot: P08922)

Localization

Cell membrane.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

264 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ROS Antibody (PD01-27)

ROS Antibody (PD01-27)

Immunohistochemistry: ROS Antibody (PD01-27) [NBP3-32917]

Immunohistochemistry: ROS Antibody (PD01-27) [NBP3-32917] - Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue with Rabbit anti-ROS antibody (NBP3-32917) at 1/200 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (NBP3-32917) at 1/200 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Applications for ROS Antibody (PD01-27)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH7.4), 0.1% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ROS1

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. (provided by RefSeq)

Long Name

ROS Proto-Oncogene 1, Receptor Tyrosine Kinase

Alternate Names

c-Ros-1, MCF3

Gene Symbol

ROS1

Additional ROS1 Products

Product Documents for ROS Antibody (PD01-27)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ROS Antibody (PD01-27)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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