RRM1 Antibody (4E4)

Novus Biologicals, part of Bio-Techne | Catalog # H00006240-M03

Novus Biologicals, part of Bio-Techne
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H00006240-M03
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4E4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RRM1 Antibodies »

Product Specifications

Immunogen

RRM1 (NP_001024, 644 a.a. ~ 753 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLN

Localization

Cytoplasmic

Specificity

RRM1 - ribonucleotide reductase M1 polypeptide

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for RRM1 Antibody (4E4)

ELISA: RRM1 Antibody (4E4) [H00006240-M03]

ELISA: RRM1 Antibody (4E4) [H00006240-M03]

ELISA: RRM1 Antibody (4E4) [H00006240-M03] - Detection limit for recombinant GST tagged RRM1 is approximately 0.3ng/ml as a capture antibody.

Applications for RRM1 Antibody (4E4)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RRM1

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Long Name

Ribonucleotide Reductase Catalytic Subunit M1

Alternate Names

RIR1, RR1

Entrez Gene IDs

6240 (Human)

Gene Symbol

RRM1

OMIM

180410 (Human)

UniProt

NP_001024 (Human)

Additional RRM1 Products

Product Documents for RRM1 Antibody (4E4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RRM1 Antibody (4E4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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