RTKN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20239

Novus Biologicals, part of Bio-Techne
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NBP2-20239
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RTKN Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human RTKN. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RTKN Antibody

Western Blot: RTKN Antibody [NBP2-20239]

Western Blot: RTKN Antibody [NBP2-20239]

Western Blot: RTKN Antibody [NBP2-20239] - RTKN antibody detects RTKN protein by western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of human RTKN-transfected 293T cells. 7.5 % SDS-PAGE. RTKN antibody dilution: 1:5000.
Immunocytochemistry/ Immunofluorescence: RTKN Antibody [NBP2-20239]

Immunocytochemistry/ Immunofluorescence: RTKN Antibody [NBP2-20239]

Immunocytochemistry/Immunofluorescence: RTKN Antibody [NBP2-20239] - RTKN antibody detects RTKN protein at cytoplasm by immunofluorescent analysis.Sample: RTKN-transfected (right) or untransfected (left) HeLa cells were fixed in ice-cold MeOH for 5 min. Green: RTKN protein stained by RTKN antibody diluted at 1:500. Blue: Hoechst 33342 staining.
Western Blot: RTKN Antibody [NBP2-20239]

Western Blot: RTKN Antibody [NBP2-20239]

Western Blot: RTKN Antibody [NBP2-20239] - Sample (20 ug of whole cell lysate) A: mouse brain 7. 5% SDS PAGE gel, diluted at 1:10000.
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Applications for RTKN Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RTKN

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

B5, rhotekin, RTKN1

Gene Symbol

RTKN

UniProt

Q9BST9 (Human)

Additional RTKN Products

Product Documents for RTKN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RTKN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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