Ryanodine Receptor 2 Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-95111

Novus Biologicals, part of Bio-Techne
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NBP2-95111-0.02ml
NBP2-95111-0.1ml
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Ryanodine Receptor 2 Antibodies »

Product Summary for Ryanodine Receptor 2 Antibody - Azide and BSA Free

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 4868-4967 of human Ryanodine Receptor 2 (NP_001026.2). EHTGQESYVWKMYQERC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Ryanodine Receptor 2 Antibody - Azide and BSA Free

Western Blot: Ryanodine Receptor 2 AntibodyAzide and BSA Free [NBP2-95111]

Western Blot: Ryanodine Receptor 2 AntibodyAzide and BSA Free [NBP2-95111]

Western Blot: Ryanodine Receptor 2 Antibody [NBP2-95111] - Analysis of extracts of mouse heart, using Ryanodine Receptor 2 .Exposure time: 90s.
Immunocytochemistry/ Immunofluorescence: Ryanodine Receptor 2 Antibody - Azide and BSA Free [NBP2-95111]

Immunocytochemistry/ Immunofluorescence: Ryanodine Receptor 2 Antibody - Azide and BSA Free [NBP2-95111]

Immunocytochemistry/Immunofluorescence: Ryanodine Receptor 2 Antibody [NBP2-95111] - Immunofluorescence analysis of U-2 OS cells using Ryanodine Receptor 2 Rabbit pAb (NBP2-95111) at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.
Immunocytochemistry/ Immunofluorescence: Ryanodine Receptor 2 Antibody - Azide and BSA Free [NBP2-95111]

Immunocytochemistry/ Immunofluorescence: Ryanodine Receptor 2 Antibody - Azide and BSA Free [NBP2-95111]

Immunocytochemistry/Immunofluorescence: Ryanodine Receptor 2 Antibody [NBP2-95111] - Analysis of mouse heart cells using RYR2 Rabbit pAb at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
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Applications for Ryanodine Receptor 2 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

Azide and BSA Free

Preservative

0.05% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Ryanodine Receptor 2

Dihydropyridine receptor (DHPR) is a surface membrane protein critical for the excitation-contraction coupling of striated muscle. DHPR and the sarcoplasmic reticulum ryanodine receptor (RyR) are two key components of the intracellular junctions, where depolarization of the surface membrane is converted into the release of Ca2+ from internal stores. The alpha1-subunit of the DHPR contains a cytoplasmic loop which is thought to be involved in the interactions with RyR. Phosphorylation of the DHPR alpha1-subunit is also thought to play a role in the functional interaction of DHPR and RyR. Mutation in DHPR alpha1 results in excitation-contraction uncoupling, leading to muscular dysgenesis, a complete inactivity in developing skeletal muscles. Cells that do not express RyR also lack excitation-contraction coupling and exhibit a severalfold reduction in Ca2+ current density.

Long Name

Ryanodine receptor 2

Alternate Names

hRYR-2, RYR-2, RyR2

Gene Symbol

RYR2

Additional Ryanodine Receptor 2 Products

Product Documents for Ryanodine Receptor 2 Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Ryanodine Receptor 2 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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