S100A9 Antibody (S100A9/1011)

Validated:

Unconjugated

Monoclonal Mouse IgM Kappa Clone # S100A9/1011

0.2 mg/ml

Recombinant human S100A9 protein (Uniprot: P06702)

Cytoplasmic, Extracellular (secreted) and Cell Surface

Recognizes a 14kDa protein, identified as S100A9 (also known as Calgranulin B or MRP-14); expressed by granulocytes, monocytes and by tissue macrophages. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This monoclonal antibody reacts with neutrophils, monocytes and macrophages, and has been shown as an important marker for identifying macrophages in tissue sections. Among cells that are now recognized as macrophages are histiocytes, Kupffer cells, osteoclasts, microglial cells, synovial type A cells, interdigitating cells, and Langerhans cells (in normal tissues) and epithelioid cells and Langerhans-type and foreign-body-type multinucleated giant cells (in inflamed tissues).

Macrophage Marker

Monoclonal

Mouse

IgM Kappa

14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

200ug/ml of antibody purified from Bioreactor Concentrate. Prepared in 10 mM PBS with 0.05% azide. Also available WITHOUT BSA at 1.0 mg/ml. (NBP3-11453)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein L or PEG purified

10 mM PBS

0.05% Sodium Azide

0.2 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.