SALM4/LRFN3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41098

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (93%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SALM4/LRFN3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the center of human LRFN3. The immunogen is located within amino acids 380 - 430 of LRFN3. Amino Acid Squence: DPPRDGDPDALTPPS

Specificity

This antibody is predicted to not cross-react with other members of the LRFN family.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SALM4/LRFN3 Antibody - BSA Free

Western Blot: SALM4/LRFN3 AntibodyBSA Free [NBP2-41098]

Western Blot: SALM4/LRFN3 AntibodyBSA Free [NBP2-41098]

Western Blot: SALM4/LRFN3 Antibody [NBP2-41098] - Western blot analysis of LRFN3 in K562 lysate with LRFN3 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: SALM4/LRFN3 Antibody - BSA Free [NBP2-41098]

Immunocytochemistry/ Immunofluorescence: SALM4/LRFN3 Antibody - BSA Free [NBP2-41098]

Immunocytochemistry/Immunofluorescence: SALM4/LRFN3 Antibody [NBP2-41098] - Mouse brain tissue with LRFN3 antibody at 20 ug/mL.
Immunohistochemistry: SALM4/LRFN3 Antibody - BSA Free [NBP2-41098]

Immunohistochemistry: SALM4/LRFN3 Antibody - BSA Free [NBP2-41098]

Immunohistochemistry: SALM4/LRFN3 Antibody [NBP2-41098] - Immunohistochemistry of LRFN3 in mouse brain tissue with LRFN3 antibody at 2.5 ug/mL.
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Applications for SALM4/LRFN3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SALM4/LRFN3

Synaptic adhesion-like molecule 4 (SALM4; also leucine-rich repeat and fibronectin type-III domain-containing protein 3 (Lrfn3) is an approximately 90 kDa member of the Lrfn family of type I transmembrane glycoproteins. Human SALM4 is synthesized as a 628 amino acid (aa) precursor that contains a 16 aa signal sequence, a 523 aa extracellular domain (ECD), a 21 aa transmembrane region, and a 68 aa cytoplasmic region. The ECD consists of six leucine-rich repeats (LRR), an IgC2-like domain, and a fibronectin type-III domain, tandemly aligned in that order. In addition, there are five potential sites for N-linked glycosylation. SALM4 and SALM5 lack a C-terminal intracellular PDZ binding domain, which is conserved among SALMs 1-3. Mature human SALM4 shares 96% aa sequence identity with mature mouse SALM4. Northern blot analysis showed that in mice, SALM4 is strongly expressed in the adult brain and is also present in the adult gastrointestinal tract and kidneys. It is distributed throughout the neuron, including the growth cone. In the developing mouse embryo, a temporal expression profile blot revealed a general increment of expression around E10.5, with weak expression detected before E10.5. SALM4, like the other SALMs, promotes neurite outgrowth. Specifically, the SALMs modify total outgrowth and neurite branching.

Long Name

Leucine-rich Repeat and Fibronectin Type III Domain Containing Protein 3

Alternate Names

FIGLER1, LRFN3

Gene Symbol

LRFN3

Additional SALM4/LRFN3 Products

Product Documents for SALM4/LRFN3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SALM4/LRFN3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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