SARM1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41180

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SARM1 Antibodies »

Product Summary for SARM1 Antibody - BSA Free

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SARM. The immunogen is located within amino acids 30 - 80 of SARM. Amino Acid Squence: AGGRGPREVSPGAGTE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Pig: (88%)

Specificity

At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SARM1 Antibody - BSA Free

Western Blot: SARM1 AntibodyBSA Free [NBP2-41180]

Western Blot: SARM1 AntibodyBSA Free [NBP2-41180]

Western Blot: SARM1 Antibody [NBP2-41180] - Analysis of SARM in Daudi cell lysate with SARM antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP2-41180]

Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP2-41180]

Immunocytochemistry/Immunofluorescence: SARM1 Antibody [NBP2-41180] - Immunofluorescence of SARM in human kidney tissue with SARM antibody at 20 ug/mL.

Applications for SARM1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1 - 2 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SARM1

Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.

Long Name

Sterile alpha and TIR Motif Containing 1

Alternate Names

SAMD2

Gene Symbol

SARM1

Additional SARM1 Products

Product Documents for SARM1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SARM1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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