Scaffold attachment factor B2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13274

Novus Biologicals, part of Bio-Techne
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NBP2-13274
NBP2-13274-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Scaffold attachment factor B2 Antibodies »

Product Summary for Scaffold attachment factor B2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: NMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEHAVDGEGFKNTLETSSLNFKVTPDIEESL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Scaffold attachment factor B2 Antibody

Immunocytochemistry/ Immunofluorescence: Scaffold attachment factor B2 Antibody [NBP2-13274]

Immunocytochemistry/ Immunofluorescence: Scaffold attachment factor B2 Antibody [NBP2-13274]

Immunocytochemistry/Immunofluorescence: Scaffold attachment factor B2 Antibody [NBP2-13274] - Staining of human cell line MCF7 shows localization to nucleoplasm, nuclear bodies & vesicles.
Immunohistochemistry-Paraffin: Scaffold attachment factor B2 Antibody [NBP2-13274]

Immunohistochemistry-Paraffin: Scaffold attachment factor B2 Antibody [NBP2-13274]

Immunohistochemistry-Paraffin: Scaffold attachment factor B2 Antibody [NBP2-13274] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells and glial cells.

Applications for Scaffold attachment factor B2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Scaffold attachment factor B2

Scaffold attachment factor B2 (SAFB2) is a chromatin associated protein that interacts with DNA elements termed S/MARs (scaffold or matrix attachment regions) but is not part of the nuclear matrix. SAFB2 is structurally and functionally similar to SAFB1 and appears to be a multifunctional protein involved in chromatin organization, mRNA processing and transcriptional regulation. SAFB2 has been demonstrated to interact with and function as a corepressor with many nuclear receptors such as estrogen receptor-alpha, PPAR-gamma, and FXR-alpha.

Alternate Names

KIAA0138SAF-B2, scaffold attachment factor B2

Gene Symbol

SAFB2

Additional Scaffold attachment factor B2 Products

Product Documents for Scaffold attachment factor B2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Scaffold attachment factor B2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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