SERCA1 ATPase Antibody (SR1006)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22005

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22005-100ul
NBP3-22005-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1006

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SERCA1 ATPase Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human SERCA1 ATPase (Uniprot #: O14983)

Specificity

Detects endogenous levels of total SERCA1 ATPase

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SERCA1 ATPase Antibody (SR1006)

Western Blot: SERCA1 ATPase Antibody (SR1006) [NBP3-22005] -

Western Blot: SERCA1 ATPase Antibody (SR1006) [NBP3-22005] - Western blot analysis using NBP3-22005 in human fetal muscle lysate.

Applications for SERCA1 ATPase Antibody (SR1006)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:1000-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SERCA1 ATPase

SERCA1 ATPase encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.

Long Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Alternate Names

ATP2A1, Calcium pump 1, EC 7.2.2.10, SERCA1, SR Ca(2+)-ATPase 1

Gene Symbol

ATP2A1

Additional SERCA1 ATPase Products

Product Documents for SERCA1 ATPase Antibody (SR1006)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SERCA1 ATPase Antibody (SR1006)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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