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Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07987

Novus Biologicals, part of Bio-Techne
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NBP3-07987-100ul
NBP3-07987-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL10697

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQEGAPHR

Epitope

QDKMEEVEAMLLPET

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697)

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Analysis in human liver and skeletal muscle tissues using NBP3-07987 antibody. Corresponding Serpin A3/alpha 1-Antichymotrypsin RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987]

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human cerebral cortex shows cytoplasmic and nuclear positivity in a subset of glial cells.

Applications for Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697)

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin A3/alpha 1-Antichymotrypsin

Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Alternate Names

alpha 1-Antichymotrypsin

Gene Symbol

SERPINA3

Additional Serpin A3/alpha 1-Antichymotrypsin Products

Product Documents for Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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