Serpin C1/Antithrombin-III Antibody (023)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89296

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89296-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 023

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Serpin C1/Antithrombin-III Antibodies »

Product Summary for Serpin C1/Antithrombin-III Antibody (023)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Serpin C1/Antithrombin-III (Accession#: NP_000479.1; Met 1-Lys 464).

Specificity

No cross-reactivity in ELISA with: Human SerpinA1Human SerpinA3Human SerpinA5Mouse SerpinF2Human SerpinF1Human SerpinD1Mouse SerpinD1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for Serpin C1/Antithrombin-III Antibody (023)

Application
Recommended Usage

ELISA

1:5000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin C1/Antithrombin-III

Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties

Alternate Names

Antithrombin-III, ATIII

Gene Symbol

SERPINC1

Additional Serpin C1/Antithrombin-III Products

Product Documents for Serpin C1/Antithrombin-III Antibody (023)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Serpin C1/Antithrombin-III Antibody (023)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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