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Serpin G1/C1 Inhibitor Antibody (18)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89738

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Sandwich ELISA Detection, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 18

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Serpin G1/C1 Inhibitor (Accession#: NP_000053.2; Met 1-Ala 500).

Specificity

No cross-reactivity in ELISA with: Human SerpinA1 / A1AT Human SerpinA3 / SERPINA3 / AACT Human SerpinA5 / PROCI Human SerpinC1 /SERPINC1/ Antithrombin-III Human SerpinD1 / SERPIND1 / HC2 Human SerpinF1 / SERPINF1 / PEDF Human SerpinF2 / SERPINF2 Human SerpinI1 / SERPINI1 / Protease inhibitor 12

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Serpin G1/C1 Inhibitor Antibody (18)

Western Blot: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738]

Western Blot: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738]

Western Blot: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738] - Lane A: HepG2 Whole Cell Lysate Lysates/proteins at 30 ug per lane.Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:55 kDa Observed band size:71 kDa
Immunoprecipitation: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738]

Immunoprecipitation: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738]

Immunoprecipitation: Serpin G1/C1 Inhibitor Antibody (18) [NBP2-89738] - Lane A:0.5 mg HepG2 Whole Cell Lysate 2 uL anti-SERPING1 rabbit monoclonal antibody and 15 ul of 50 % Protein G agarose. Primary antibody:Anti-SERPING1 rabbit monoclonal antibody,at 1:100 dilution Secondary antibody:Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions.Predicted band size: 55 kDa Observed band size: 100 kDa

Applications for Serpin G1/C1 Inhibitor Antibody (18)

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunoprecipitation

0.5-2 uL/mg of lysate

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin G1/C1 Inhibitor

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

Alternate Names

C1 Inhibitor

Gene Symbol

SERPING1

Additional Serpin G1/C1 Inhibitor Products

Product Documents for Serpin G1/C1 Inhibitor Antibody (18)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Serpin G1/C1 Inhibitor Antibody (18)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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