SETD7/9 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56664

Novus Biologicals, part of Bio-Techne
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NB100-56664
NB100-56664SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Chromatin Immunoprecipitation (ChIP), Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Chemotaxis

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all SETD7/9 Antibodies »

Product Specifications

Immunogen

Two synthethic peptides corresponding to amino acids 131-145 (GEVNEDGEMTGEKIA) and 336-352 (GYDHSPPGKSGPEAPEW) of human SETD7 were used as immunogen for this antibody.

Specificity

This is specific for Set7/9 (a histone H3 lysine 4 methyltransferase) and does not recognize PR-Set7 (a histone H4 lysine 20 methyltransferase).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SETD7/9 Antibody

Western Blot: SETD7/9 Antibody [NB100-56664]

Western Blot: SETD7/9 Antibody [NB100-56664]

Western Blot: SETD7/9 Antibody [NB100-56664] - Whole cell extract from MCF7 cells. Image from verified customer review.
Immunohistochemistry-Paraffin: SETD7/9 Antibody [NB100-56664]

Immunohistochemistry-Paraffin: SETD7/9 Antibody [NB100-56664]

Immunohistochemistry-Paraffin: SETD7/9 Antibody [NB100-56664] - Analysis of human small instestine using SETD7 antibody at 1:100.
Western Blot: SETD7/9 Antibody [NB100-56664]

Western Blot: SETD7/9 Antibody [NB100-56664]

Western Blot: SETD7/9 Antibody [NB100-56664] - Analysis of SETD7 in A) MCF7 and B) HeLa lysate using SETD7 antibody at 1:500.

Applications for SETD7/9 Antibody

Application
Recommended Usage

Chromatin Immunoprecipitation (ChIP)

1:10-1:500

Immunohistochemistry-Paraffin

1:100

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NB100-56664 in the following applications:

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Neat whole antisera

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SETD7/9

Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.

Alternate Names

EC 2.1.1.43, H3-K4-HMTase SETD7, histone H3-lysine 4-specific methyltransferase, histone-lysine N-methyltransferase SETD7, KIAA1717SET domain-containing protein 7, KMT7FLJ21193, Lysine N-methyltransferase 7, SET domain containing (lysine methyltransferase) 7, SET7/9Histone H3-K4 methyltransferase SETD7, SET7Set9, SET9

Entrez Gene IDs

73251 (Mouse); 288653 (Rat)

Gene Symbol

SETD7

UniProt

Q8WTS6 (Human)

Additional SETD7/9 Products

Product Documents for SETD7/9 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SETD7/9 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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